Last edited by Kajilar
Friday, May 15, 2020 | History

5 edition of Biology of the NMDA Receptor (Frontiers in Neuroscience) found in the catalog.

Biology of the NMDA Receptor (Frontiers in Neuroscience)

by Antonius M. VanDongen

  • 15 Want to read
  • 5 Currently reading

Published by CRC .
Written in English

    Subjects:
  • Medical / Neuroscience,
  • Life Sciences - Cytology,
  • Neuroscience,
  • Pharmacology,
  • Medical,
  • Medical / Nursing

  • The Physical Object
    FormatHardcover
    ID Numbers
    Open LibraryOL11816443M
    ISBN 101420044141
    ISBN 109781420044140

      NMDA-type glutamate receptors are ligand-gated ion channels that mediate a major component of excitatory neurotransmission in the central nervous system (CNS). They are widely distributed at all stages of development and are critically involved in normal brain functions, including neuronal development and synaptic by: NMDA Receptor Protocols offers today's scientists powerful methods for basic research on NMDA receptor structure and function, as well as enormous opportunities for clinical investigation toward the development of novel bioactive compounds. "synopsis" may belong to another edition of Price Range: $ - $

    NMDA receptors function as gated Ca 2+ channels to permit the flow of Ca 2+ and other positively charged ions across the cytoplasmic membrane, 10 that is, influx of Ca 2+ and Na +, and efflux of K +.Unlike voltage-gated Ca 2+ channels, depolarization alone is not sufficient to open the NMDA receptor–gated Ca 2+ channel. On the other hand, glutamate binding alone also is not sufficient to Author: Qiang Gu, Cheng Wang. The NMDA receptors are essential for neuronal development, synaptic plasticity, learning, and cell survival. It covers molecular, cellular, anatomical, biochemical, and behavioral aspects, to highlight their distinctive regulatory properties, their functional significance, and their therapeutic potential in a . The progress of research in the excitatory amino acid (EAA) field over the last forty years is well documented. The field had its origin in the discovery by Hayashi () of the convulsive effects of l-glutamate and l-aspartate in mammalian brain, and the demonstration later in the decade of the depolarizing and excitatory actions of these amino acids on single central neurones.

    : NMDA Receptor Protocols (Methods in Molecular Biology) () and a great selection of similar New, Used and Collectible Books available now at great Range: $ - $ N-methyl-d-aspartate receptor (NMDAR) is an ionotropic glutamate receptor which is found in nerve is named after the synthetic agonist to whom it is selectively sensitive, N-methyl-d-aspartate (NMDA). The NMDA receptor is an ionotropic receptor comprising of an extracellular amino terminus sphere, 3 transmembrane spheres, a reentrant cringle, intracellular carboxyl sphere, and a ligand adhering sphere. Specific signalling molecules/phosphorylation sites involved in trafficking of the NMDA receptor are thought to act upon its surface look.


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Biology of the NMDA Receptor (Frontiers in Neuroscience) by Antonius M. VanDongen Download PDF EPUB FB2

SyntaxTextGen not activatedThis book comprises an pdf and comprehensive coverage of the NMDA receptor. The NMDA receptor is an important protein in the brain which is involved in physiological processes such as synaptic transmission and synaptic plasticity which may underlie learning and memory.

The physiology of N-methyl-d-aspartate (NMDA) receptors is fundamental to brain development and function. NMDA receptors are ionotropic glutamate receptors that function as heterotetramers Cited by: Cutting-edge and practical, NMDA Receptors: Ebook and Protocols is a valuable resource that discusses the ebook of the currently-used methods, the importance of NMDARs and their complexity, and the progress that has already been made.

This book will be of interest to scientists, clinicians, and industry professionals working in this field.